Low-Cost Method to Monitor Patient Adherence to HIV Antiretroviral Therapy Using Multiplex Cathepsin Zymography
نویسندگان
چکیده
منابع مشابه
Low-Cost Method to Monitor Patient Adherence to HIV Antiretroviral Therapy Using Multiplex Cathepsin Zymography.
Monitoring patient adherence to HIV antiretroviral therapy (ART) by patient survey is inherently error prone, justifying a need for objective, biological measures affordable in low-resource settings where HIV/AIDS epidemic is highest. In preliminary studies conducted in Ethiopia and South Africa, we observed loss of cysteine cathepsin activity in peripheral blood mononuclear cells of HIV-positi...
متن کاملAdherence to antiretroviral therapy.
INTRODUCTION The goal of HAART is to achieve maximal and durable suppression of virus replication. Adherence plays a very important role in success of antiretroviral therapy. AIMS AND OBJECTIVES To find out the rate of adherence and factors that influence adherence to antiretroviral therapy (ART). MATERIAL AND METHODS The present study was conducted in the Department of Medicine in a tertia...
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The non-adherence to the highly active antiretroviral therapy (HAART) is considered one of the most threatening risks for the effectiveness of the treatment of the person with HIV/AIDS on the individual plan and for the resistance-virus dissemination on the collective plan. The objective of this study was to analyze, through a literature review, the predicting factors of non-adherence to the HA...
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Superior adherence to HIV-1 antiretroviral therapy is a mainstay of successful HIV management. Studies performed in the early era of highly active antiretroviral therapy demonstrated the need for > or =95% adherence in order to achieve and sustain viral suppression. High rates of viral suppression have been observed at more moderate levels of adherence with newer antiretroviral regimens. The te...
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ژورنال
عنوان ژورنال: Molecular Biotechnology
سال: 2015
ISSN: 1073-6085,1559-0305
DOI: 10.1007/s12033-015-9903-0